How to Get Xyrem (Sodium Oxybate) Covered by Cigna in Michigan: Complete Decision Tree & Appeals Guide 2025
Answer Box: Getting Xyrem Covered by Cigna in Michigan
Quick path to approval: Cigna requires prior authorization for Xyrem (sodium oxybate) in Michigan, plus mandatory REMS enrollment for both prescriber and patient. Three key steps: 1) Confirm narcolepsy diagnosis with sleep studies (PSG + MSLT), 2) Document failed first-line therapy (stimulants/