How to Renew Xyrem (Sodium Oxybate) Coverage with Blue Cross Blue Shield of Michigan: Timeline, Documentation, and Appeal Guide
Answer Box: Renewing Xyrem Coverage with BCBS Michigan
Start your Xyrem renewal 2-4 weeks before your current authorization expires. BCBS Michigan typically approves Xyrem for 6-12 month periods and requires updated clinical documentation showing continued benefit. Submit through your provider's portal or fax with current ESS scores, cataplexy