Renewing Signifor / Signifor LAR (Pasireotide) Approval with Cigna in Virginia: 2025 Requirements, Timeline & Evidence Guide
Answer Box: Renewing Your Signifor LAR Coverage
Cigna typically approves Signifor LAR renewals for 12 months when you demonstrate ongoing clinical response. For Cushing's disease, you'll need recent UFC (urinary free cortisol) showing reduction from baseline. For acromegaly, provide age-adjusted IGF-1 normalization or GH <1.