Blue Cross Blue Shield Michigan's Coverage Criteria for Pyrukynd (mitapivat): What Counts as "Medically Necessary"?
Answer Box: Getting Pyrukynd Covered in Michigan
Blue Cross Blue Shield of Michigan requires prior authorization for Pyrukynd (mitapivat), typically with these three key steps: (1) Confirmed PKLR gene variants proving pyruvate kinase deficiency, (2) Clinical severity documentation (hemoglobin ≤10 g/dL or ≥6 transfusions in 12 months), and (3)