How to Get Synagis (Palivizumab) Covered by Blue Cross Blue Shield of Michigan: Complete Forms, Appeals & Contact Guide

Answer Box: To get Synagis (palivizumab) covered by Blue Cross Blue Shield of Michigan, you need prior authorization using their Medication Authorization Request Form. Submit via fax (1-877-325-5979) or Availity portal with clinical documentation proving high-risk RSV status per AAP guidelines. If denied, file internal appeal within 180 days, then external review with Michigan DIFS within 127 days. Start by calling BCBS provider services at 1-800-344-8525 for current forms and requirements.

Table of Contents

Coverage at a Glance

Requirement What It Means Where to Find It Source
Prior Authorization Required Must get approval before treatment BCBS Michigan PA Drug List BCBS Michigan
High-Risk Criteria AAP-defined eligibility only Medical Policy 2026884 BCBS Michigan Policy
Season Limits Nov 1 - Mar 31 (up to 5 doses) Provider Manual BCBS Michigan
Site of Care Office/home preferred over hospital Medical Policy BCBS Michigan
Appeals Deadline 180 days from denial Member Appeal Form BCBS Michigan Appeals
External Review 127 days after final denial Michigan DIFS Michigan DIFS

Step-by-Step: Fastest Path to Approval

1. Verify Eligibility (Day 1)

  • Check patient meets AAP high-risk criteria (premature infants, chronic lung disease, congenital heart disease)
  • Confirm RSV season timing (November 1 - March 31 in Michigan)
  • Call BCBS provider services: 1-800-344-8525

2. Gather Documentation (Days 1-2)

  • Complete medical history and diagnosis codes
  • Prior therapy records (if applicable)
  • Specialist consultations (cardiology/pulmonology when relevant)
  • Current clinical notes supporting high-risk status

3. Submit Prior Authorization (Day 3)

4. Follow Up (Days 7-10)

  • Check authorization status through provider portal
  • Call Medical Drug Helpdesk: 1-800-437-3803 if no response

5. If Denied: Internal Appeal (Within 180 days)

  • Use Member Appeal Form
  • Include additional clinical justification
  • Submit via mail or fax (addresses on form)

6. External Review if Needed (Within 127 days of final denial)

  • File with Michigan DIFS: 877-999-6442
  • Use DIFS External Review Form
  • Include physician's urgent medical necessity letter if expedited

7. Coordinate Specialty Pharmacy

  • Work with Walgreens Specialty Pharmacy: 1-866-515-1355
  • Arrange office delivery and administration schedule

Required Forms and Documentation

Primary Authorization Form

The BCBS Michigan Synagis Medication Authorization Request Form requires:

  • Patient demographics and insurance information
  • Diagnosis with ICD-10 codes
  • Clinical justification for high-risk status
  • Requested dosing schedule and administration site
  • Provider signature and contact information

Supporting Documentation Checklist

  • Medical records documenting high-risk condition
  • Specialist reports (if cardiac or pulmonary involvement)
  • Hospital discharge summaries (for premature infants)
  • Growth charts and gestational age documentation
  • Prior RSV hospitalization records (if applicable)
Clinician Corner: Your medical necessity letter should clearly state the specific AAP criteria the patient meets, reference supporting clinical guidelines, and explain why Synagis is preferred over supportive care alone. Include specific risk factors like gestational age, chronic lung disease severity, or hemodynamically significant congenital heart disease.

Submission Portals and Channels

Electronic Submission

  • Availity Portal: Primary method for most BCBS Michigan providers
  • E-referral System: Required for Medicare Plus Blue members
  • Log in at bcbsm.com/login and navigate to provider tools

Fax Submission

  • Prior Authorization Fax: 1-877-325-5979
  • Include complete authorization form and all supporting documents
  • Use cover sheet with patient name, DOB, and member ID

Mail Submission (if required)

Check current mailing address on authorization form, as addresses may change. Always verify with provider services before mailing time-sensitive requests.

Common Denial Reasons & Solutions

Denial Reason How to Overturn Required Documentation
Doesn't meet high-risk criteria Provide detailed clinical evidence Specialist consultation, growth charts, medical history
Missing documentation Submit complete medical records Hospital records, discharge summaries, diagnostic reports
No prior authorization File retroactive PA request Clinical justification for urgency, medical necessity letter
Exceeds dose limits Request exception for extended season Physician letter explaining continued risk, clinical monitoring plan
Inappropriate site of care Justify hospital administration Medical complexity requiring hospital-level monitoring

Appeals Process for BCBS Michigan

Internal Appeal (First Level)

  • Timeline: Must file within 180 days of denial
  • Form: BCBS Michigan Member Appeal Form
  • Decision time: 60 days for post-service, 30 days for prior authorization
  • Submit to: Address provided on appeal form

External Review (Second Level)

When internal appeals fail, Michigan offers robust external review rights:

  • Timeline: 127 days from final internal denial
  • Contact: Michigan DIFS at 877-999-6442
  • Online form: DIFS External Review Portal
  • Decision time: 60 days standard, 72 hours expedited
  • Cost: Free to consumers
Tip: For urgent cases during RSV season, request expedited external review with a physician's letter stating delay would seriously jeopardize the patient's health.

Key Contact Numbers

BCBS Michigan Provider Services

  • Physicians/Professionals: 1-800-344-8525
  • Hospitals/Facilities: 1-800-249-5103
  • Medical Drug Helpdesk: 1-800-437-3803
  • Hours: Monday-Friday, 8 AM-12 PM and 1-5 PM

Member Services

  • General Member Services: Number on member ID card
  • Pharmacy Benefits: OptumRx 1-855-811-2223 (PPO), 1-844-642-9087 (HMO)

Medicaid Plans

  • Blue Cross Complete: 1-800-228-8554 (24/7)
  • Pharmacy Questions: 1-888-288-3231

Michigan Regulatory Support

Specialty Pharmacy Coordination

Walgreens Specialty Pharmacy

BCBS Michigan contracts with Walgreens Specialty for Synagis distribution:

  • Phone: 1-866-515-1355
  • Process: Call after PA approval to arrange delivery
  • Delivery: Ships directly to provider office
  • Billing: Uses HCPCS code J2505 under medical benefit

Administration Planning

  • Schedule monthly injections during RSV season
  • Coordinate with pediatric office for proper storage
  • Plan for potential dose adjustments based on weight

Counterforce Health specializes in turning insurance denials into successful appeals by analyzing denial letters, plan policies, and clinical notes to create targeted, evidence-backed appeals. Our platform helps patients and providers navigate complex prior authorization requirements and appeals processes for medications like Synagis.

Michigan External Review Process

Michigan's Patient's Right to Independent Review Act provides strong consumer protections:

Filing Requirements

  • Complete insurer's internal appeal process first
  • Submit within 127 days of final denial
  • Include final adverse determination letter
  • Provide supporting medical documentation

Review Process

  • DIFS assigns case to Independent Review Organization (IRO)
  • IRO uses independent medical experts
  • Reviews medical necessity and policy compliance
  • Decision is binding on the insurer

Expedited Review

Available when delay would seriously jeopardize health:

  • Requires physician's written statement
  • Decision within 72 hours
  • Particularly relevant during RSV season for high-risk infants

Cost Considerations

Synagis Pricing

  • Approximate cost: $1,820 per 50mg vial (Connecticut state WAC, 2025)
  • Typical course: 5 monthly doses during RSV season
  • Total seasonal cost: ~$9,100+ depending on dosing

Financial Assistance

  • Manufacturer Support: Contact Sobi/AstraZeneca for patient assistance programs
  • State Programs: Michigan Medicaid covers for eligible children
  • Foundation Grants: Research rare disease foundations for additional support

FAQ

How long does BCBS Michigan prior authorization take for Synagis? Standard PA decisions are made within 14 business days. Urgent requests during RSV season may be expedited to 72 hours with proper clinical justification.

What if Synagis is not on my plan's formulary? Submit a formulary exception request with the PA form, including medical necessity documentation and evidence that no covered alternatives are appropriate.

Can I appeal if I missed the RSV season window? Yes, but you'll need strong clinical justification for why treatment is still medically necessary outside the standard November-March season.

Does step therapy apply to Synagis? Generally no, as Synagis is for prevention in high-risk infants. However, plans may require consideration of nirsevimab (Beyfortus) when available and appropriate.

What happens if my child needs more than 5 doses? Submit a request for additional doses with clinical justification, such as extended RSV season, cardiac surgery requiring restart, or continued high-risk status.

Can I get expedited appeals during RSV season? Yes, both BCBS Michigan and Michigan DIFS offer expedited review processes when delay would jeopardize the patient's health during active RSV season.


Getting specialized medications approved can be challenging, but Counterforce Health helps streamline the process by creating targeted appeals that address specific denial reasons with evidence-backed arguments tailored to your plan's requirements.

Sources & Further Reading


Disclaimer: This information is for educational purposes only and does not constitute medical or legal advice. Insurance policies and procedures change frequently. Always verify current requirements with your specific plan and consult healthcare providers for medical decisions. For personalized assistance with insurance appeals and prior authorizations, contact Counterforce Health.

Powered by Counterforce Health—AI that turns drug denials into evidence-based appeals patients and clinicians can submit today.