How Long Does It Take to Get Humira Approved by Blue Cross Blue Shield in Michigan? Complete Timeline & Appeal Guide

Answer Box: Getting Humira Approved by BCBS Michigan

Blue Cross Blue Shield of Michigan requires prior authorization for Humira, with decisions typically made within 15 calendar days (72 hours for urgent cases). The fastest path involves: 1) Complete TB/hepatitis B screening, 2) Try preferred biosimilars first (step therapy), and 3) Submit PA via Availity portal with detailed clinical documentation. If denied, you have 127 days to file external review with Michigan DIFS. Start today by checking your BCBS Michigan formulary status and gathering required screening results.

Table of Contents

What Affects Humira Approval Timeline

Several factors determine how quickly BCBS Michigan approves your Humira prescription:

Benefit Type & Plan Design

  • Commercial plans: Standard 15-day review period
  • Medicare Advantage: May follow Medicare Part D timelines
  • Medicaid managed care: Different process through state program

Documentation Completeness Your approval speed depends heavily on having all required elements upfront:

  • Complete TB screening (TST or IGRA within 6-12 months)
  • Hepatitis B panel (HBsAg, anti-HBs, anti-HBc)
  • Step therapy documentation (biosimilar trials/failures)
  • Diagnosis with appropriate ICD-10 codes
  • Clinical notes supporting medical necessity

Step Therapy Requirements BCBS Michigan prioritizes adalimumab biosimilars over brand Humira in 2024. You'll need documented trials of preferred alternatives like Amjevita or Cyltezo unless contraindicated.

Tip: Electronic submissions through Availity/NovoLogix process faster than fax submissions and provide real-time status updates.

Pre-Submission Preparation (0-2 Days)

Essential Checklist

Before your doctor submits the prior authorization:

Required Screening Tests

  • Tuberculosis screening: TST (≥5mm = positive) or IGRA within past year
  • Hepatitis B panel: HBsAg, anti-HBs, anti-HBc
  • Complete blood count and liver function tests
  • Chest X-ray (if TB risk factors present)

Clinical Documentation

  • Confirmed diagnosis with ICD-10 code
  • Disease activity scores or severity measures
  • Prior medication trials with dates, doses, and outcomes
  • Contraindications to preferred biosimilars (if applicable)
  • Treatment goals and monitoring plan

Insurance Verification

  • Current BCBS Michigan member ID
  • Confirm Humira formulary status on your specific plan
  • Verify specialty pharmacy network requirements
Note: BCBS Michigan requires Humira to be dispensed through Walgreens Specialty Pharmacy at 1-866-515-1355.

Submission to Initial Review (1-5 Days)

How BCBS Michigan Processes Requests

Electronic Submission (Recommended)

  • Portal: Availity with NovoLogix tool
  • Processing time: 1-2 business days to reach reviewer
  • Real-time status tracking available

Alternative Methods

  • Fax: Check current BCBS Michigan PA fax number
  • Phone: 1-800-437-3803 for urgent cases
  • Mail: Slower processing (5-7 days)

Initial Review Checklist Reviewers verify:

  1. Member eligibility and benefit coverage
  2. Formulary status and tier placement
  3. Step therapy compliance
  4. Required screening completion
  5. Clinical appropriateness per policy

Expedited Review Process

For urgent cases where delay could harm your health, BCBS Michigan must decide within 72 hours. Your doctor must document why waiting poses serious risk.

Decision Window & Outcomes

Standard Timeline: 15 Calendar Days

Typical Outcomes:

  • Approved: Full coverage with any applicable copay/coinsurance
  • Approved with modifications: Different dose, quantity, or duration
  • Denied: Detailed reason provided with appeal rights

Reading Your Approval Letter Look for:

  • Authorization number for pharmacy
  • Approved quantity and days supply
  • Refill limitations
  • Expiration date (typically 12 months)

If Additional Information Needed

BCBS Michigan may request:

  • Peer-to-peer review with prescribing physician
  • Additional clinical records
  • Specialist consultation notes
  • Updated lab results

Response timeframe: Typically 5-7 business days to provide requested information.

If Denied: Michigan Appeal Process

Internal Appeal (First Step)

Timeline: Must file within 60 days of denial Processing: BCBS Michigan has 30 days for preservice appeals

Required Documents:

  • Original denial letter
  • Prescriber's medical necessity letter
  • Updated clinical documentation
  • Guidelines supporting off-label use (if applicable)

External Review Through Michigan DIFS

If internal appeal fails, Michigan's Department of Insurance and Financial Services provides independent review.

Key Deadlines:

  • 127 days to file after final internal denial
  • DIFS notifies parties within 14 days
  • Decision typically within 56 days (can extend to 84 days)

Filing Options:

Required Forms:

  • Health Care Request for External Review
  • Copy of denial letter
  • Physician certification (if experimental/investigational claim)

Expedited External Review

For urgent cases, Michigan DIFS decides within 72 hours with physician attestation of medical urgency.

Renewal Cycles & Ongoing Authorization

Annual Reauthorization

BCBS Michigan requires Humira reauthorization every 12 months. Your doctor must submit:

  • Updated clinical assessment
  • Current disease activity measures
  • Continued medical necessity documentation
  • Any new contraindications to biosimilars

Timing: Submit renewal 30-45 days before expiration to avoid therapy interruption.

What Speeds Renewals

  • Stable clinical response documented
  • No significant adverse events
  • Continued contraindication to preferred alternatives
  • Electronic submission with complete records

Timeline Visual & Milestones

Milestone Timeline Your Action
Screening completion 0-2 days Schedule TB/HBV tests
PA submission Day 1 Doctor submits via Availity
Initial review Days 2-5 Monitor portal for updates
Additional info request Days 6-10 Respond within 5-7 days
Final decision Day 15 Review approval/denial letter
Internal appeal (if denied) Within 60 days File with supporting docs
External review filing Within 127 days Submit to Michigan DIFS
DIFS decision 28-56 days Binding determination

Time-Saving Tips for Faster Approval

Portal Usage Best Practices

Availity/NovoLogix Advantages:

  • Real-time status tracking
  • Faster processing than fax
  • Automatic confirmation receipts
  • Direct communication with reviewers

Bundled Evidence Strategy

Submit comprehensive documentation upfront:

  • Complete screening results
  • Detailed prior therapy history
  • Specialist consultation notes
  • Relevant imaging or lab trends
  • Treatment response measures

Direct Specialty Routing

For complex cases, request:

  • Pharmacy & Therapeutics committee review
  • Clinical pharmacist consultation
  • Medical director review
From our advocates: We've seen fastest approvals when providers submit everything electronically through Availity with a comprehensive medical necessity letter addressing each step therapy requirement specifically. Cases with missing TB screening or incomplete biosimilar trial documentation consistently face delays or denials.

Common Denial Reasons & Solutions

Denial Reason Solution
Step therapy not met Document biosimilar trials with specific dates, doses, outcomes
Missing TB screening Submit TST/IGRA results within past 12 months
Incomplete HBV screening Provide HBsAg, anti-HBs, anti-HBc results
"Not medically necessary" Submit disease activity scores, functional assessments
Quantity limits exceeded Justify dosing with weight-based calculations or guidelines
Non-formulary status File formulary exception with clinical rationale

Medical Necessity Letter Template Elements

Your doctor's letter should address:

  1. Specific diagnosis with ICD-10 code
  2. Disease severity and functional impact
  3. Prior treatments tried with outcomes
  4. Why biosimilars are inappropriate
  5. Expected benefits of Humira
  6. Monitoring plan and safety measures

FAQ: BCBS Michigan Humira Coverage

How long does BCBS Michigan take for Humira prior authorization? Standard review is 15 calendar days; urgent cases get 72-hour decisions. Electronic submissions via Availity typically process fastest.

What if Humira isn't on my formulary? You can file a formulary exception request with clinical documentation showing medical necessity and why covered alternatives aren't appropriate.

Do I have to try biosimilars first? Yes, BCBS Michigan requires step therapy through preferred adalimumab biosimilars unless you have documented contraindications or prior failures.

Can I get expedited review? Yes, if your doctor certifies that waiting would seriously jeopardize your health or ability to regain function.

What happens if my appeal is denied? You can file for external review with Michigan DIFS within 127 days. Their decision is binding on BCBS Michigan.

How often do I need reauthorization? Humira requires annual reauthorization. Submit renewal requests 30-45 days before expiration.

What specialty pharmacy must I use? BCBS Michigan requires Walgreens Specialty Pharmacy (1-866-515-1355) for Humira dispensing.

Are there patient assistance programs? Yes, AbbVie offers Humira Complete support program, and various foundations provide grants for eligible patients.


Counterforce Health specializes in turning insurance denials into successful appeals by creating targeted, evidence-backed rebuttal letters. Our platform analyzes denial reasons, plan policies, and clinical documentation to draft point-by-point appeals that address each payer's specific requirements. For complex cases like Humira approvals involving step therapy and specialty pharmacy requirements, having the right documentation and appeal strategy can make the difference between coverage and continued denials. Learn more about our prior authorization and appeals support.

Sources & Further Reading


This information is for educational purposes only and does not constitute medical or legal advice. Always consult with your healthcare provider and insurance plan for specific coverage decisions. Coverage policies and requirements may change; verify current information with BCBS Michigan and Michigan DIFS before making decisions.

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