Do You Qualify for Chenodal (chenodiol) Coverage by UnitedHealthcare in Illinois? Decision Tree & Next Steps

Answer Box: Getting Chenodal Covered by UnitedHealthcare in Illinois

You likely qualify for Chenodal (chenodiol) coverage if you have radiolucent gallstones confirmed by imaging, cannot undergo surgery, and have tried ursodiol first (or have documented contraindications). UnitedHealthcare requires prior authorization with a 72-hour standard decision timeline.

Fastest path to approval:

  1. Gather imaging showing radiolucent stones and surgical risk documentation
  2. Document ursodiol trial failure or contraindication
  3. Submit PA through UnitedHealthcare Provider Portal with gastroenterologist prescription

Start today: Contact your gastroenterologist to request prior authorization if you meet the criteria above.


Table of Contents


How to Use This Decision Tree

This guide helps you determine your eligibility for Chenodal (chenodiol) coverage through UnitedHealthcare in Illinois and provides specific next steps based on your situation. Work through the eligibility questions in order, then follow the action plan for your category.

UnitedHealthcare classifies Chenodal as a Tier 3 (non-preferred brand) medication requiring prior authorization for all prescriptions. The good news? Standard PA decisions come within 72 hours, and expedited requests are processed within 24 hours for urgent cases.


Eligibility Triage: Do You Qualify?

Answer these questions to determine your coverage pathway:

1. Diagnosis Confirmation

  • Do you have radiolucent (cholesterol) gallstones confirmed by recent imaging? (ultrasound or CT within 6 months)
  • Is your gallbladder well-opacifying on contrast studies? (Non-visualizing gallbladders are contraindicated)

2. Surgical Status

  • Are you unable to undergo cholecystectomy due to surgical risk? (age, systemic disease, or other contraindications)
  • Do you have documentation from a specialist confirming increased surgical risk?

3. Step Therapy Requirements

  • Have you completed a 6-month trial of ursodiol at 8-10 mg/kg/day?
  • OR do you have documented contraindications to ursodiol?
  • Can you provide exact start/stop dates and reason for discontinuation?

4. Prescriber Requirements

  • Is your prescription from a gastroenterologist? (or physician experienced in gallstone dissolution therapy)

5. Safety Criteria

  • Do you have normal baseline liver function tests?
  • Are you not pregnant? (Chenodal is contraindicated in pregnancy)
  • Do you lack preexisting hepatic impairment or bile duct abnormalities?

If You're "Likely Eligible"

Congratulations! You answered "yes" to most criteria above. Here's your document checklist and submission path:

Document Checklist

  • Recent imaging (ultrasound/CT) showing radiolucent gallstones
  • Contrast study confirming well-opacifying gallbladder
  • Specialist documentation of surgical contraindications
  • Ursodiol trial records with dates and failure reason
  • Baseline liver function tests (normal results)
  • Gastroenterologist prescription with weight-based dosing
  • Patient weight and calculated mg/kg dose (not exceeding 16-18 mg/kg/day)

Submission Path

  1. Provider submits PA through UnitedHealthcare Provider Portal with all documentation
  2. Timeline: 72 hours for standard review, 24 hours for expedited
  3. Authorization period: 12 months if approved
  4. Follow-up: Liver function monitoring required for renewals
From our advocates: We've seen the strongest approvals when gastroenterologists include a detailed letter explaining why surgery isn't appropriate and how the patient meets all step therapy criteria. The more specific the clinical documentation, the faster the approval typically comes.

If You're "Possibly Eligible"

You meet some but not all criteria. Here's what to request and track:

Missing Imaging Studies

  • Request: Updated ultrasound or CT scan within 6 months
  • Track: Ensure radiology report specifically mentions "radiolucent" or "cholesterol" stones
  • Timeline: Schedule within 2-4 weeks, then resubmit PA

Incomplete Step Therapy

  • Request: Complete documentation of ursodiol trial or formal contraindication assessment
  • Track: Exact dates, dosing, and specific reason for discontinuation
  • Timeline: If ongoing trial, complete 6 months before reapplying

Surgical Risk Documentation

  • Request: Formal surgical consultation or specialist assessment
  • Track: Written documentation of specific contraindications to cholecystectomy
  • Timeline: 2-3 weeks for consultation, then immediate PA submission

If You're "Not Yet Eligible"

Don't lose hope. Here are alternatives to discuss with your provider:

Alternative Treatments

  • Ursodiol (ursodeoxycholic acid): First-line therapy for gallstone dissolution
  • Surgical consultation: Second opinion on operative candidacy
  • Symptom management: Medical therapy for biliary colic while pursuing approval

Preparing for Exception Requests

Even if you don't meet standard criteria, UnitedHealthcare may approve exceptions with compelling clinical documentation. Discuss with your gastroenterologist:

  • Unique clinical circumstances
  • Failed alternative approaches
  • Urgent medical need

Counterforce Health specializes in turning insurance denials into targeted, evidence-backed appeals by identifying the specific denial basis and crafting point-by-point rebuttals aligned to each plan's own rules.


If Your Request Gets Denied

Illinois provides strong appeal rights with specific timelines. Here's your pathway:

Internal Appeals (First Level)

  • Timeline: 180 days from denial to file
  • Decision: 15 business days for pre-service requests
  • Expedited: 24 hours for urgent cases
  • Submit to: UnitedHealthcare appeals department (address on denial letter)

External Review (Independent)

  • Eligibility: After exhausting internal appeals
  • Timeline: 30 days from final denial to request (shorter than many states)
  • Process: Independent Review Organization (IRO) with physician reviewer
  • Decision: 5 business days after IRO receives all materials
  • Cost: Free to consumers
Note: Illinois' 30-day deadline for external review is stricter than many states' 4-month window, so act promptly after appeal denials.

Coverage Requirements at a Glance

Requirement What It Means Where to Find It Source
Prior Authorization Required for all Chenodal prescriptions UnitedHealthcare Provider Portal OptumRx PA Requirements
Formulary Tier Tier 3 (non-preferred brand) Member formulary documents UnitedHealthcare Formulary
Step Therapy Ursodiol trial required (effective April 1, 2025) PA submission forms UHC Step Therapy Policy
Prescriber Gastroenterologist or experienced physician PA forms Coverage policy documents
Imaging Radiolucent stones on recent study Radiology reports Medical necessity criteria
Duration 12-month authorization Approval letters Standard authorization periods

Appeals Playbook for Illinois

Level 1: Internal Appeal

  • Deadline: 180 days from denial
  • Submit to: UnitedHealthcare appeals address on denial letter
  • Required: Completed appeal form, denial letter, supporting documentation
  • Timeline: 15 business days for decision

Level 2: External Review

  • Deadline: 30 days from final internal denial
  • Submit to: Illinois Department of Insurance
  • Required: External review form, denial letters, medical records
  • Timeline: 5 business days for IRO decision
  • Cost: Free

Illinois Consumer Assistance


Common Denial Reasons & How to Fix Them

Denial Reason How to Overturn
"Step therapy not completed" Provide ursodiol trial documentation with exact dates and failure reason
"Not medically necessary" Submit imaging confirming radiolucent stones and surgical risk documentation
"Off-label use" Ensure prescription is for FDA-approved indication (gallstone dissolution)
"Quantity exceeds limits" Verify dosing doesn't exceed 16-18 mg/kg/day with weight calculations
"Missing documentation" Complete PA form with all required attachments per checklist
"Non-visualizing gallbladder" Obtain contrast study showing well-opacifying gallbladder

FAQ

How long does UnitedHealthcare PA take in Illinois? Standard prior authorization decisions come within 72 hours, with expedited requests processed in 24 hours for urgent cases.

What if Chenodal is non-formulary on my plan? Chenodal is typically Tier 3 (non-preferred brand) but covered with prior authorization. Non-formulary exceptions may be possible with compelling clinical documentation.

Can I request an expedited appeal in Illinois? Yes, if a delay would seriously jeopardize your health. Internal appeals must be decided within 24 hours for expedited cases.

Does step therapy apply if I failed ursodiol outside Illinois? Yes, but you can use that prior failure documentation. Ensure you have exact dates and specific reason for discontinuation.

What counts as medical necessity for Chenodal? Radiolucent gallstones confirmed by imaging, surgical ineligibility, completed ursodiol trial (or contraindication), and prescription from experienced physician.

How much does Chenodal cost with UnitedHealthcare? As a Tier 3 medication, expect higher copays than preferred brands. Check your specific plan's formulary for exact costs.


When navigating complex prior authorization requirements, Counterforce Health helps patients, clinicians, and specialty pharmacies get prescription drugs approved by turning insurance denials into targeted, evidence-backed appeals. The platform identifies the specific denial basis and drafts point-by-point rebuttals aligned to each plan's own coverage rules, pulling the right citations and clinical evidence to support your case.


Sources & Further Reading


Disclaimer: This information is for educational purposes only and does not constitute medical or legal advice. Coverage policies and requirements may change. Always verify current information with UnitedHealthcare and consult your healthcare provider for medical decisions. For assistance with Illinois insurance appeals, contact the Illinois Department of Insurance at 877-527-9431.

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